Skin Substitutes

Advanced Skin Substitutes for Modern Wound Care

Explore a powerful portfolio of regenerative grafts and wound coverings designed to accelerate healing and restore skin integrity.

🌿 Featured Products

At PSP360+, we connect clinics with high-performance skin substitutes and grafts that go beyond standard dressings. From amniotic membranes to collagen-based scaffolds, our curated lineup supports conservative therapy and advanced wound healing protocols.

Whether you're dealing with diabetic ulcers, burns, or surgical wounds, these products are engineered to optimize healing outcomes with minimal complications.

🌿 Amniotic-Based Products

🧬 Collagen & ECM-Based Wraps

💧Hydrated/

Hydrogel Variants

🛡️ Hybrid or Multi-layered Options

🌿 Amniotic-Based Skin Substitute

✅ AmnioAmp

🧬 Type:

Dehydrated Human Amniotic Membrane Allograft

✨ What Is It?

Allograft Patch -

A biologic skin graft from human placental tissue, AmnioAmp is packed with natural healing agents like growth factors and anti-inflammatory proteins.

🩹 What It’s Used For?

~ Diabetic ulcers

~ Post-surgical wounds

~ Chronic non-healing wounds

💡 Why Clinics Love It:

~ Promotes rapid tissue repair
~ Easy to apply — no hydration needed
~ Naturally reduces inflammation and pain
~ Can help reduce scarring

📦 How It Works:

Applied directly to the wound, it rehydrates with natural wound fluid and activates cellular repair.

📊 Clinical Backing:

Shown to accelerate healing and improve closure rates in tough-to-treat wounds.

✅ Xcell Amnio

🧬 Type:

Cryopreserved Amniotic Membrane

✨ What Is It?

Is a membrane allograft that may be used as a therapeutic active barrier agent in numerous clinical applications. Preserves the full biological integrity of fresh amniotic tissue to supercharge healing.

🩹 What It’s Used For?

~ Pressure ulcers

~ Burns

~ Radiation wounds

💡 Why Clinics Love It:

~ Maintains active growth factors

~ Supports natural tissue regeneration

~ Lowers infection risk

~ Flexible and easy to place

📦 How It Works:

Stored cryogenically, it’s thawed and applied directly over wounds to deliver regenerative proteins.

📊 Clinical Backing:

Extensively studied in wound care centers with consistent healing improvements.

✅ BioDFence

🧬 Type:

Dehydrated Human Amniotic Membrane Allograft

✨ What Is It?

An amniotic barrier that protects wounds and stimulates repair with zero immune rejection. Resorbable adhesion barrier allograft derived from the human amnion that provides a structural barrier to reduce scar tissue formation.

🩹 What It’s Used For?

~ Surgical incisions

~ Trauma wounds

~ Chronic ulcers

💡 Why Clinics Love It:

~ Rehydrates instantly

~ No sutures required

~ Excellent conformability

~ Long shelf life

📦 How It Works:

Placed on wound and covered with secondary dressing — that's it.

📊 Clinical Backing:

Outperforms standard dressings in healing time and scar appearance.

🧬 Collagen & ECM-Based Wraps

✅ Cytal

🧬 Type:

Porcine-derived ECM Scaffold

✨ What Is It?

A natural scaffold made from pig tissue that mimics the body’s own healing framework.

🩹 What It’s Used For?

~ Bedsores

~ Diabetic wounds

~ Partial-thickness wounds

💡 Why Clinics Love It:

~ Biocompatible and ready-to-use

~ Promotes angiogenesis

~ Breaks down safely in the body

~ Supports granulation

📦 How It Works:

Forms a structure that cells use to rebuild healthy skin from the inside out.

📊 Clinical Backing:

Shown to support faster granulation and closure compared to foam dressings.

✅ PriMatrix

🧬 Type:

Fetal Bovine Dermal Matrix

✨ What Is It?

A non-crosslinked, natural collagen mesh that integrates into damaged skin and promotes regrowth.

🩹 What It’s Used For?

~ Reconstructive wounds

~ Diabetic ulcers

~ Skin tears

💡 Why Clinics Love It:

~ High compatibility

~ Supports vascular

in-growth

~ No prep required

~ Flexible and resorbable

📦 How It Works:

Placed onto the wound and left to integrate — no suture needed.

📊 Clinical Backing:

Favored in plastic surgery and wound centers for regenerative outcomes.

✅ Integra Bilayer

🧬 Type:

Bilayer Matrix Dressing

✨ What Is It?

A dual-layer dressing with collagen for healing and silicone to control moisture loss.

🩹 What It’s Used For?

~ Full-thickness burns

~ Skin graft sites

~ Surgical closures

💡 Why Clinics Love It:

~ Offers scaffold and moisture protection

~ Can be used in complex wounds

~ Long-standing reputation in burn care

📦 How It Works:

Apply with inner layer on wound bed; outer layer controls moisture loss.

📊 Clinical Backing:

Gold standard in dermal regeneration for burn victims.

💧 Hydrated/Hydrogel Variants

✅ AmnioExcel Plus

🧬 Type:

Hydrated Allograft

✨ What Is It?

Ready-to-use allograft that retains natural amniotic components to promote moist healing.

🩹 What It’s Used For?

~ Scrapes and minor ulcers

~ Skin irritations

~ Moist wound therapy

💡 Why Clinics Love It:

~ No hydration step

~ Natural healing environment

~ Antimicrobial properties

📦 How It Works:

Unpack and place — its moisture locks into the wound bed instantly.

📊 Clinical Backing:

Reduces healing time in superficial ulcers by up to 40%.

✅ AmnioBand

🧬 Type:

Dehydrated Allograft

✨ What Is It?

A rehydratable band that forms a natural regenerative cover over chronic wounds.

🩹 What It’s Used For?

~ Surgical incisions
~ Chronic diabetic ulcers
~ Skin flaps

💡 Why Clinics Love It:

~ Easy to apply

~ Boosts epithelial growth

~ Helps reduce inflammation

📦 How It Works:

Place over the wound, add moisture if needed — then let it do its work.

📊 Clinical Backing:

Widely used in outpatient wound centers with strong success metrics.

🛡️ Hybrid or Multi-Layered Options

Amniotic-Based or Hybrid Substitute (pending manufacturer specs)

Amniotic + Collagen Hybrid (likely composite)

✅ DermACELL

🧬 Type:

Aseptic Human Dermis

✨ What Is It?

A clean, natural human skin graft designed to support advanced tissue repair.

🩹 What It’s Used For?

~ Trauma wounds

~ Breast reconstruction

~ Surgical repair

💡 Why Clinics Love It:

~ Promotes angiogenesis

~ Integrates fully with tissue

~ Long shelf life

📦 How It Works:

Surgeon places DermACELL over complex wounds or surgical areas to support durable healing.

📊 Clinical Backing:

Used in over 100,000 procedures nationwide.

✅ FlexHD

🧬 Type:

Human Acellular Dermis

✨ What Is It?

Preserves human dermal structure to provide strength and cellular integration in reconstruction cases.

🩹 What It’s Used For?

~ Hernia repairs

~ Breast reconstructions

~ Complex closures

💡 Why Clinics Love It:

~ Proven strength and elasticity

~ Facilitates durable closure

~ Custom sizing options

📦 How It Works:

Implanted surgically and becomes part of the patient’s own tissue network.

📊 Clinical Backing:

Backed by a decade of reconstructive use with excellent cosmetic results.

✅ Simplimax

🧬 Type:

Advanced Wound Healing Matrix

✨ What Is It?

Simplimax is a next-gen wound covering designed to simplify care while maximizing healing. Its matrix structure mimics the skin’s natural environment and supports full-thickness tissue regeneration.

🩹 What It’s Used For?

~ Chronic venous ulcers

~ Post-surgical wounds

~ Non-healing diabetic wounds

💡 Why Clinics Love It:

~ Combines bioactive healing with
structural support

~ Easy to trim and place

~ Reduces inflammation at the wound site

~ May require fewer dressing changes

📦 How It Works:

Conforms to wound beds, creating a stable base for cell migration and vascular in-growth.

📊 Clinical Backing:

Praised for its effectiveness in difficult-to-heal wounds with minimal dressing fatigue.

AmchoMatrix

🧬 Type:

Composite Regenerative Scaffold

✨ What Is It?

AmchoMatrix brings together two powerful healing forces — amniotic tissue and collagen — into one composite scaffold. It’s designed to stimulate repair while maintaining structural integrity in challenging wounds.

🩹 What It’s Used For?

~ Surgical closures

~ Severe burns

~ Complex wound beds

💡 Why Clinics Love It:

~ Combines regenerative signaling with
tissue support

~ Excellent for layered wound care

~ Maintains moisture without sloughing

~ Ideal for advanced outpatient procedures

📦 How It Works:

Laid onto the wound bed, the matrix creates a synergistic healing environment that fosters epithelial cell growth and capillary formation.

📊 Clinical Backing:

Used widely in trauma centers and burn units with superior granulation outcomes.

🔬 Conservative Therapy First: The Power of Collagen Prep

🧠 Collegen Is The Prerequisite For Skin Subs Wound Care

Before grafts, before advanced wound care…
collagen gets the skin ready to heal.

For many patients, the healing journey starts with something simple — daily collagen therapy.

Applied directly to the wound, this powdered or gel-based treatment helps stimulate natural repair and prepares the site for more advanced care like skin substitutes or grafts.

At PSP360+, we don’t just drop products on your desk — we help you build effective wound care protocols.

Conservative therapy is often the key to qualifying patients for biologic treatment and ensuring the best clinical outcomes.

We assist with DME coverage, patient education, and billing compliance—

so you can deliver care without the guesswork.

➡️ Stay tuned for our upcoming DME Collagen Protocol Page —

or book a call today to get early access to our guide.

🚀 Why PSP360+?

Because your clinic deserves more than just billing support.

It deserves a growth partner that brings strategy, tools, funding, and marketing to the table. Let’s transform your practice into a high-performing, cash-flowing powerhouse.

Let's get you started with your free billing assessment (cha-ching 💸).

Once you see those revenue gaps start to close—yep, it happens fast thanks to daily billing—we’ll circle back to plug you into Step 2: your Google Map Pack takeover.

Then we can move into our core services (Steps 3-5) to get you the boosting your practice needs.

Because what’s the point of boosting your cash flow if patients still can’t find you?

Let’s fill your books and get you ranking like a local legend. 🎯

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Every step of our process is built on full HIPAA compliance and rock-solid operational integrity. But what really sets PSP apart? We’ve never had a single client leave us — ever.

When practices partner with us, they stay.

That’s the PSP360+ promise.

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PSP360+ is the official marketing arm of a nationally recognized medical billing firm. We leverage advanced billing and coding strategies to enhance accuracy, streamline operations, and boost revenue for healthcare practices across the country.

PSP360+ operates as a DBA of The Mustard Seed Group LLC, providing specialized solutions to healthcare providers nationwide.